Open a Project Dashboard for one of your important projects. Avoid checking email and work on your most important tasks.
When you do check on email, group your Inbox by priority (View > Current View > ClearContext Prioritized by Category) and review only your highest priority messages (in red and green).
Use the MessageContext to see emails, appointments and other related tasks to get the full context for the item you are working on.
Only touch your high priority messages once. Even though you are glancing at these messages throughout the day, make sure that you act on any email you open.
For additional tips for using the ClearContext Daily Workflow, see the following blog posts: